The European Commission has launched two new calls under the 'Digital, Industry and Space' cluster of the Horizon Europe Work Programme, allocating €307.3 million to bolster Europe's digital innovation and competitiveness. A total of €221.8 million is dedicated to an initiative focusing on the development of trustworthy artificial intelligence (AI) services, innovative data services, and securing of EU strategic autonomy. The call will fund projects contributing to AI development, including actions supporting the Apply AI Strategy, robotics, quantum technologies, photonics, and virtual worlds. An additional €85.5 million is available for the second call, which will support open strategic autonomy in digital and emerging technologies and raw materials, focusing on topics like next-gen AI agents, robotics for industrial and service applications, and the development of new materials with enhanced sensing functionalities. These initiatives aim to drive sustainable innovation and European leadership in strategic digital technologies, aligning with the Commission's Competitiveness Compass. The application window remains open until April 15, 2026.